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Ith EP2 and EP4 receptors expressed by immune cells results in raise in cyclic AMP, activates protein kinase A and3. Molecular Mediators of Immune SuppressionTo regulate immune response, MSCs and MDSCs use a set of mediators and mechanisms, which they partially share with other immune regulatory cells. Within this section, we summarize the principle mechanisms whereby MSCs and MDSCs mediate immune

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